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The possible mechanism of the cell homing effect is the following: the high level of SDF-1 secreted by tumor cells serve as a chemoattractant gradient for MSCs, expressing CXCR4 receptor [355]
PLoS Biol (2006) 4(11):e374.10.1371/journal.pbio.0040374 116 SzegezdiELogueSEGormanAMSamaliA
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